The Department of Endocrinology, 
The KgA1c Paradox: Widening the spectrum.
- Department of Endocrinology, Bharti Hospital, Karnal, India
- University Center for Research & Development, Chandigarh University, Mohali, India.
- Department of Medicine, Alchemist Hospital, Panchkula, India.
- Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India
- Non communicable disease unit, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
JPMA. The Journal of the Pakistan Medical Association Vol. 74 · Issue 7 · pp. 1378-1379
PMID 39028078 DOI 10.47391/jpma.24-54
Cite This Article
Sanjay Kalra, Suneet Verma, Nitin Kapoor. The KgA1c Paradox: Widening the spectrum. JPMA. The Journal of the Pakistan Medical Association. 2024;74(7):1378-1379. doi:10.47391/jpma.24-54
Abstract
The term KgA1c paradox is used to describe the unwanted rise in weight that occurs when HbA1c is controlled using conventional therapy. We highlight facets of pathophysiology, prevention, pharmacology, person centred care, and epidemiology, which correspond to the concept of KgA1c paradox. We suggest a novel index, KgA1c product [(BMI) x (HbA1c)], which can be used to evaluate efficacy of drugs, and assess metabolic control in persons with diabetes.
Keywords
- Diabesity
- diabetes
- HbA1c
- metabolic syndrome
- overweight
- obesity
