The Department of Endocrinology, 
Growth hormone storm following infarction of a residual growth hormone secreting pituitary macroadenoma.
- Department of Neurosurgery, Christian Medical College, Vellore, India.
- Department of Pathology, Christian Medical College, Vellore, India.
- Department of Radiation Oncology, Christian Medical College, Vellore, India.
- Department of Endocrinology, Christian Medical College, Vellore, India.
British journal of neurosurgery Vol. 38 · Issue 4 · pp. 983-986
PMID 34615430 DOI 10.1080/02688697.2021.1988055
Cite This Article
Abhijit Goyal-Honavar, Sauradeep Sarkar, Geeta Chacko, Rajesh Balakrishnan, H S Asha, Ari G Chacko. Growth hormone storm following infarction of a residual growth hormone secreting pituitary macroadenoma. British journal of neurosurgery. 2024;38(4):983-986. doi:10.1080/02688697.2021.1988055
Abstract
BACKGROUND: Thyrotroph pituitary adenomas have been reported to be a rare cause of 'thyroid storms', causing myriad metabolic and autonomic disturbances. In this case, we describe the second reported case in literature of a 'GH storm' in an infarcted somatotroph adenoma.
CASE DESCRIPTION: We describe a residual invasive somatotroph macroadenoma that underwent infarction, producing a dramatic elevation in serum GH levels. While infarction of adenomas may in some cases lead to remission, the patient went on to require re-surgery and re-radiation due to growth of the residual viable tumour.
CONCLUSIONS: 'GH storms' are rare but interesting events that may occur in somatotroph adenomas. Infarction or apoplexy must be considered when managing residual adenomas.
Keywords
- Somatotroph
- growth hormone
- infarction
- pituitary adenoma
- storm
