The Department of Endocrinology, 
Classification of Non-Insulin Glucose Lowering Drugs.
- Department of Endocrinology, Bharti Hospital, Karnal, New Delhi, India.
- Department of Endocrinology, Dayanand Medical College and Hospital, Ludhiana, India.
- Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore (TN) -632004, India, and Non Communicable Disease Unit, Melbourne School of Population and Global Health, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia.
JPMA. The Journal of the Pakistan Medical Association Vol. 72 · Issue 1 · pp. 181-182
PMID 35099465 DOI 10.47391/jpma.22-003
Cite This Article
Sanjay Kalra, Saurabh Arora, Nitin Kapoor. Classification of Non-Insulin Glucose Lowering Drugs. JPMA. The Journal of the Pakistan Medical Association. 2022;72(1):181-182. doi:10.47391/jpma.22-003
Abstract
The ever-changing scenario of diabetes care, especially pharmacotherapy, calls for a framework to help classify non-insulin glucose drugs. Such a taxonomic structure should be of contemporary relevance as well as futuristic in vision; scholarly in intent but easy to understand; and based on pathophysiologic principles while being useful for the clinician. We propose a rubric which lists four classes of non-insulin glucose lowering drugs; insulin secretagogues, insulin sensitizers, calorie restriction mimetics, and calorie restrictors. This classification serves the need of students and teachers as well as pharmacologists and clinicians alike.
Keywords
- Alpha glucosidase inhibitors
- DPP4i
- GLP1RA
- liraglutide
- pharmacotherapy sulfonylureas
- semaglutide
- SGLT2i.
