The Department of Endocrinology, 
The Insulin: Glucagon Ratio and Obesity.
- Department of Endocrinology, Bharti Hospital, Karnal, India
- University Center for Research & Development, Chandigarh University, India.
- Department of Endocrinology, Dayanand Medical College and Hospital, Ludhiana, India.
- Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India
- Non communicable disease unit, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia ).
JPMA. The Journal of the Pakistan Medical Association Vol. 73 · Issue 3 · pp. 709-710
PMID 36932791 DOI 10.47391/jpma.23-20
Cite This Article
Sanjay Kalra, Saurabh Arora, Nitin Kapoor. The Insulin: Glucagon Ratio and Obesity. JPMA. The Journal of the Pakistan Medical Association. 2023;73(3):709-710. doi:10.47391/jpma.23-20
Abstract
This communication discusses the physiology and pathology of the insulin glucagon ratio, with respect to obesity. Though high insulin levels are associated with obesity in this manuscript the authors specifically highlight its role in the causation and clinical management of obesity. It suggests that the term insulin glucagon ratio be used in preference to glucagon insulin ratio, and shares insights which may be helpful in informing future research.
Keywords
- Diabetes
- overweight
- obesity
- metabolic fulcrum
- metabolic seesaw
- ominous octet of obesity
